Dihydrotestosterone - The Key Element in Male Hair Reduction

Dihydrotestosterone (DHT) is a potent and highly energetic androgen implicated for man pattern hair loss. Dihydrotestosterone is produced mainly in the prostate gland, souffrance, adrenal glands and tresses follicles. The organization of dihydrotestosterone involved testosterone as a prohormone. Testosterone is metabolized by either of the two types of isoenzymes: 5-alpha reductase type I actually and 5-alpha reductase type II changing it to a more active dihydro- form.

Androgen target cells are the sites of dihydrotestosterone formation which include the androgen dependent and androgen sensitive regions in the body. In the androgen sensitive region, the nuclear membrane and microsomes are involved in the conversion process. Although, testosterone is produced mainly in the testes, production of dihydrotestosterone occurs any place in the body where testosterone has entered the cells of the vom männlichen geschlechtshormon dependent tissue. In the head, the androgen dependent areas include the frontotemporal region, the crown and the vertex. Essentially, these are the websites where hair tumble occurs at the onset of male pattern tresses loss.

In the androgen dependent regions on the scalp, testosterone is transformed to dihydrotestosterone. Dihydrotestosterone then binds to the androgen receptors in the hair follicles. The androgen receptors actually bind both testo-sterone and dihydrotestosterone. Yet , the dihydro- form has higher affinity to and dissociates more slowly from the receptors. Thus, higher levels of the hormone are retained in the receptors. The existence of the androgens in the hair follicles actually facilitates hair growth. Nevertheless, in genetically predisposed individuals, high amounts of DHT can prevent hair growth, even completely stopping it. As a result, the damaged area on the scalp slowly but surely thins and may change completely bald. Even if baldness have masteron not yet took place, the afflicted may still look bald because of progressive miniaturization of tresses. Normally, this type of curly hair loss starts during growing up where the body produces high levels of androgenic hormone or testosterone.

Dihydrotestosterone can only exert its negative effects on predisposed individuals. Male pattern hair loss is heritable. Folks who inherit the gene that predisposes the condition become susceptible to the action of DHT. They will are likely to experience hair shedding during puberty nonetheless they may well not really notice it until after thirty where significant amount of hair was lost. Typically the condition impacts more than 50 percent of men, but the same condition is also determined in women.

At present, the male pattern hair reduction has no cure. People, however, can find treatments that can stop hair loss effectively. Since the role of DHT has already been recognized and widely accepted, the suggested treatment for the condition is the one that addresses the challenge with DHT. The DHT levels on the scalp should be maintained at levels where it cannot cause harm to the head of hair follicles. This particular can be done by instituting treatments that block the production of the hormone such as treatments that prevent the enzyme that catalyzes the conversion process. The drugs minoxidil and finasteride are known as DHT blockers because they work mainly by blocking the conversion process. Both drugs are proven effective in stopping male pattern curly hair loss. They can also opt for natural treatments that blocks DHT and promotes hair regrowth.